In full compliance with Next Generation Risk Assessment regulations,

The main principles of these ‘next generation’ risk assessments state that the methods used for safety evaluation need to be:

Five steps to develop a compliant CPSR

As seasoned professionals, we prioritize confidentiality and handle sensitive information with high NDA practices and ultra-secured VPN IT files management. To determine the safety related to each ingredient, we analyze its identification, function, and quantification.

Stability testing ensures that the functionality and aesthetics of the product are not adversely impacted during its intended shelf-life and consumer use. Testing can be conducted under controlled accelerated or real-time conditions. Packaging clearance is also evaluated.

Microbiology testing in cosmetics development ensures product safety, quality, and compliance with industry standards. It assesses antimicrobial protection, monitors raw materials, and evaluates the impact on skin microbiota.
As regards general problems of identification, ingredients requiring a “definition” including any impurities that they contain which are of toxicological significance (e.g., toxic sub-components, residual solvents, heavy metals, etc.) and the ingredients authorized in the annexes to the Cosmetics Directive should be specified using discriminant analytical techniques such as HPLC, GC/MS, NMR, etc.

In this part, the amount of the substance and the frequency of human exposure to the substance are determined (including specific groups at potential risk, e.g. children, pregnant women, etc.) based on label specifications.
Our toxicologist team will analyze the toxicological profile of each ingredient and determine a specific Margin of Safety (“MoS”) to fully assess the safety related to cosmetic exposure.

This assessment is crucial because it certifies the safety of a product before it is placed on the EU market. Our ERT toxicologist redacts this CPSR Part B section, which includes labeled warnings, usage instructions, a reasoning, and a safety report conclusion. Based on all the cosmetic safety information, our ERT expert determines whether to approve the product.

Hypothesis on the biological mechanisms of the effects of the cosmetic
Assessments of the mode, duration and frequency of the exposure to the cosmetic substance

Benefits: All available methods and strategies are used with logic, transparency and explicit documentation